Wuhan Fine Biotech Co., Ltd.'s EPCAM antibody is a Mouse monoclonal antibody. The EPCAM antibody was generated using EPCAM, and epithelial cell adhesion molecule as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Epithelial cell adhesion molecule(EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target.(PMID: 20837599; 19249674; 21576002; 22647938)